Elastase

For digestion of native elastin
概要
Elastase is a serine protease consisting of a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges (Shotton & Hartley). Elastase is synthesized as a zymogen (proelastase) and is converted to the active form by limited trypsin proteolysis at its N-terminal. Elastase preferentially cleaves the peptide bond of C-terminal neutral, non-aromatic amino acid residues (Schellenberger et al.). Elastase is frequently used in combination with other proteases such as collagenase and trypsin to digest fibrous tissues because of its ability to digest native elastin.
Subtype
Enzymatic
Alternative Names
Elastoproteinase; Lysosomal elastase; Pancreatic elastase I; Pancreatopeptidase E
Cell Type
Epithelial Cells, Myogenic Stem and Progenitor Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Area of Interest
Cancer Research, Endothelial Cell Biology, Epithelial Cell Biology, Immunology, Stem Cell Biology
Molecular Weight
26.0 kDa
技术资料
Document Type 产品名称 Catalog # Lot # 语言
Product Information Sheet Elastase 07453, 07454 All English
Safety Data Sheet Elastase 07454 All English
数据及文献
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