SU5402
MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
概要
SU5402 is a potent and selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), fibroblast growth factor receptor 1 (FGFR-1), and platelet-derived growth factor receptor beta (PDGFRB) with IC50 = 0.02, 0.03, and 0.51 µM, respectively (Sun et al.).
Alternative Names
Not applicable
Cell Type
Cancer Cells and Cell Lines, Hybridomas, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Maintenance
Area of Interest
Antibody Development, Cancer Research, Disease Modeling, Hybridoma Generation, Immunology, Stem Cell Biology
CAS Number
215543-92-3
Chemical Formula
C₁₇H₁₆N₂O₃
Molecular Weight
296.3 g/mol
Purity
≥ 95%
Pathway
MEK/ERK
Target
FGFR, PDGFR
技术资料
| Document Type | 产品名称 | Catalog # | Lot # | 语言 |
|---|---|---|---|---|
| Product Information Sheet 1 | SU5402 | 73912, 73914 | For orders placed 2019-11-26 or earlier | English |
| Product Information Sheet 2 | SU5402 | 73912, 73914 | For orders placed 2019-11-27 or later | English |
| Safety Data Sheet | SU5402 | 73912, 73914 | All | English |
数据及文献