CellAdhere™ Type I Collagen, Bovine, Solution

Type I Collagen is the most abundant type of collagen in the human body and is a major structural protein prevalent in skin, bone, tendon, and other fibrous connective tissues. All collagens are characterized by a secondary protein structure consisting of three polypeptide chains wrapped around one another in a triple helical arrangement. The different types of collagen vary in the primary amino acid sequence of their polypeptide chains, with type I collagen being comprised of two identical α1(I) chains and one α2(I) chain that spontaneously form the triple helix in solution.

CellAdhere™ Type I Collagen, Bovine, Solution is prepared from collagen extracted from bovine hide and contains a high monomer content. It is supplied at a concentration of approximately 6 mg/mL (0.6%) aqueous solution in 0.01 M HCl (pH at about 2.0). Starting material was isolated from a closed herd and purified using a highly controlled manufacturing process. This process contains validated steps to ensure inactivation of possible prion and/or viral contaminants. Product is sterility tested. Endotoxin level is 0.1 EU/mL or less, as assayed by Limulus Amoebocyte Lysate assay.