ArciTect™ sgRNA

ArciTect™ sgRNA is a custom single guide RNA (sgRNA) for CRISPR-Cas9 genome editing. ArciTect™ sgRNA contains a user-specified 19- to 21-base sequence complementary to the target genomic location. ArciTect™ sgRNA must be designed directly upstream of a protospacer adjacent motif (PAM) site (5’-NGG-3’). It contains 2'-O-methyl and phosphorothioate modifications at the first two 5' and 3' terminal residues for optimal stability and editing efficiency.