RosetteSep™ Anti-Human IgE Tetramer

The RosetteSep™ Anti-Human IgE Tetramer Cocktail is designed to deplete IgE-bearing cells (e.g. basophilic and mast cells) from whole blood. Unwanted cells are targeted for removal with Tetrameric Antibody Complexes recognizing IgE and glycophorin A on red blood cells (RBCs). When centrifuged over a buoyant density medium such as Lymphoprep™ (Catalog #07801), the unwanted cells pellet along with the RBCs. The purified non-IgE cells are present as a highly enriched population at the interface between the plasma and the buoyant density medium.