Anti-Mouse CD43 Antibody, Clone R2/60
Rat monoclonal IgM antibody against mouse CD43
概要
The R2/60 antibody reacts with mouse CD43, a type I transmembrane sialoglycoprotein expressed on the surface of most hematopoietic cells including thymocytes, T cells, B cells, NK cells, monocytes, granulocytes, platelets, and hematopoietic progenitor cells. CD43 binds ligands such as CD54 and CD169 (siglec-1) and plays regulatory roles in cell adhesion, activation, and survival. CD43 exhibits two different glycoforms; a 115 kDa form, and an activation-associated 130 kDa form, both of which are detected by the R2/60 antibody.
Subtype
Primary Antibodies
Target Antigen
CD43
Reactive Species
Mouse
Conjugation
Biotin
Host Species
Rat
Cell Type
B Cells, Dendritic Cells, Granulocytes and Subsets, Hematopoietic Stem and Progenitor Cells, Macrophages, Monocytes, Myeloid Cells, NK Cells, Plasma, Platelets, T Cells
Application
Cell Isolation, Flow Cytometry, Functional Assay, Western Blotting
Area of Interest
Immunology, Stem Cell Biology
技术资料
| Document Type | 产品名称 | Catalog # | Lot # | 语言 |
|---|---|---|---|---|
| Product Information Sheet | Anti-Mouse CD43 Antibody, Clone R2/60, Biotin | 60042BT, 60042BT.1 | All | English |
| Safety Data Sheet | Anti-Mouse CD43 Antibody, Clone R2/60, Biotin | 60042BT, 60042BT.1 | All | English |
数据及文献
Data
Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD43 Antibody, Clone R2/60, Biotin, followed by streptavidin (SAV) APC (filled histogram), or a biotin-conjugated rat IgM isotype control antibody, followed by SAV APC (solid line histogram).