Anti-Human HLA-DR Antibody, Clone LN3

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR

概要技术资料数据及文献

概要

The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II antigen encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein composed of one α (36 kDa) and one β (27 kDa) subunit. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T cells.

Primary Antibodies

HLA-DR

HLA class II histocompatibility antigen, HLA-DR alpha, HLA-DRA, HLA DRA1, HLA DR1B, HLA DR3B, HLA DRB1, HLA DRB3, HLA DRB4, HLA DRB5, HLADR4B, HLADRA1, HLADRB, Major histocompatibility class II, MHC II, MHC class II, MHC class II antigen DRA, MLRW

Rhesus, Human

Alexa Fluor 488, FITC, PE, Unconjugated

Mouse

B Cells, Dendritic Cells, Macrophages, Monocytes, Other, T Cells

Flow Cytometry, Functional Assay, Immunohistochemistry

HLA, Immunology, Infectious Diseases, Transplantation Research

LN3

3122/3123

IgG2b, kappa

技术资料

Document Type	产品名称	Catalog #	Lot #	语言
Product Information Sheet	Anti-Human HLA-DR Antibody, Clone LN3	60164	All	English
Product Information Sheet	Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488	60164AD	All	English
Product Information Sheet	Anti-Human HLA-DR Antibody, Clone LN3, FITC	60164FI, 60164FI.1	All	English
Product Information Sheet	Anti-Human HLA-DR Antibody, Clone LN3, PE	60164PE, 60164PE.1	All	English
Safety Data Sheet	Anti-Human HLA-DR Antibody, Clone LN3	60164	All	English
Safety Data Sheet	Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488	60164AD	All	English
Safety Data Sheet	Anti-Human HLA-DR Antibody, Clone LN3, FITC	60164FI, 60164FI.1	All	English
Safety Data Sheet	Anti-Human HLA-DR Antibody, Clone LN3, PE	60164PE, 60164PE.1	All	English

数据及文献

Data

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, followed by an anti-mouse IgG2b antibody, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11 (Catalog #60072), followed by an antimouse IgG2b antibody, PE (solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, FITC (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, FITC (Catalog #60072FI; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, PE (Catalog #60072PE; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488 (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, Alexa Fluor® 488 (Catalog #60072AD; solid line histogram).